abstract：:Potential therapeutic benefits of dietary n-3 fatty acids are presently evaluated in arteriosclerotic and chronic inflammatory diseases. Because some other long-chain fatty acids inhibit intestinal fluid absorption, the effects of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on fluid and electrolyte tran...

journal_title：Zeitschrift fur Gastroenterologie

authors： Loeschke K,Schreiner J,Oberst G

更新日期：1991-05-01 00:00:00

abstract：:This article gives an overview on possible new pharmacological tools to modify gastrointestinal motility and/or secretion. The characterization of new subclasses of classical neurotransmitter receptors and of peptidergic receptors offer a new approach for the development of new therapeutic agents. Using molecular biol...

journal_title：Zeitschrift fur Gastroenterologie

authors： Allescher HD

更新日期：1991-04-01 00:00:00

abstract：:20 H. pylori-positive patients with gastric or duodenal ulcer disease (n = 16, one with proof of gastric cancer obtained by histology) or severe non-ulcer dyspepsia (n = 4) were entered in a pilot study to examine the effect of a combination of omeprazole (40 mg) before breakfast and ciprofloxacin (2 x 500 mg) 1 hour ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Labenz J,Gyenes E,Peitz U,Börsch G

更新日期：1991-04-01 00:00:00

abstract：:A computerized documentation system for upper gastrointestinal endoscopy is described. It is easy and convenient to use. Data are continuously monitored and endoscopy records automatically regenerated. Records of previous examinations are rapidly retrieved and printed. Basic statistics are integrated. ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Nguyen HN,Walker S,Bode JC

更新日期：1991-03-01 00:00:00

abstract：:The results of preoperative ultrasound investigations were compared with the intraoperative findings in 42 patients (27 women, 15 men) operated on because of tumours of the cecum or colon ascendens. In 34 of 42 patients (i.e. 81%) the tumour could be correctly diagnosed by ultrasound. In 3 cases the investigator was n...

journal_title：Zeitschrift fur Gastroenterologie

authors： Grün R,Wagner E,Tomsik H,Sodomann CP,Girona J

更新日期：1991-02-01 00:00:00

abstract：:The present study was designed to determine in humans the dose of CCK which suppresses food intake. 18 male subjects received in randomized order either i.v. saline or Thr28 Nle31 CCK 25-33 (CCK-9) at 100 or 500 pmol/kgh, respectively. In addition, 7 subjects received CCK together with the opiate receptor antagonist n...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schick RR,Schusdziarra V,Mössner J,Neuberger J,Schröder B,Segmüller R,Maier V,Classen M

更新日期：1991-02-01 00:00:00

abstract：:In this randomized clinical study the effect of 300 mg ranitidine given either after an early evening meal (abt. 6 p.m.) (n = 136) or at bedtime (abt. 10 p.m.) (n = 145) was investigated in 279 patients with an acute duodenal ulcer (79 women, 200 men, age median 40 years). To provide a double blind design, patients of...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schmidtke-Schrezenmeier G,Klingmann J,Pabst G,Geerke H,Koch EM

更新日期：1990-12-01 00:00:00

abstract：:From 3/1982 to 12/1989 773 patient underwent an elective Cholezystectomy at the Surgical University Hospital of Ulm. In 87% of cases the indication was a symptomatic cholelithiasis, the mean age being 55.4 years for females and 56.6 years for males. Intraoperative complications were rare (2.8%) and of a technical natu...

journal_title：Zeitschrift fur Gastroenterologie

authors： Orth K,Haas S,Oettinger W,Beger HG

更新日期：1990-11-01 00:00:00

abstract：:Our case report on a 26-year-old male suffering from epigastric pain for several years should emphasize the fact, that even a rare congenital malformation like the annular pancreas must seriously discussed as a reason for the so called unspecific abdominal pain. Embryological development, age of manifestation, symptom...

journal_title：Zeitschrift fur Gastroenterologie

authors： Bozkurt T,Butsch B,Lederer PC,Lux G

更新日期：1990-08-01 00:00:00

abstract：:A patient with multiple hamartoma syndrome or Cowden's disease with multiple gastrointestinal polyps and malignant melanoma is presented. The syndrome is characterized by hamartomatous tumors of the skin, fibrocystic disease of the breasts, gastrointestinal polyps and disease of the thyroid gland such as goiter and ad...

journal_title：Zeitschrift fur Gastroenterologie

authors： Petritsch W,Pristautz H,Schreiber F,Stauber R,Kullnig P,Höfler H,Smolle J

更新日期：1990-07-01 00:00:00

abstract：:Video Endoscopy and Video Sonography are new developments in the field of endoscopy. They will start a structural change of the common endoscopy unit. This article shall give an overview about new development ways and their consequences for the next years in the field of Video Endoscopy. ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Stettin J

更新日期：1990-06-01 00:00:00

abstract：:Severe chronic pancreatitis can be easily diagnosed by means of pancreatic function tests and/or imaging procedures, whereas the mild form of the disease or its early stages are more difficult to detect and are often only retrospectively diagnosed. The reliability of imaging procedures depends mainly on the experience...

journal_title：Zeitschrift fur Gastroenterologie

authors： Lankisch PG,Staritz M,Freise J

更新日期：1990-05-01 00:00:00

abstract：:Between 1981 and 1987 5434 patients were studied by ERCP in Allgemeines Krankenhaus Hamburg-Barmbeck. 26 (i.e. 0.43%) suffered from Mirizze syndrome with the triad of cholelithiasis, cholecystitis and obstructive biliary disease. They were classified in four different types according to the variable localisation and o...

journal_title：Zeitschrift fur Gastroenterologie

authors： Meyer GJ,Runge D,Gebhardt J

更新日期：1990-04-01 00:00:00

abstract：:We studied the effect of two peptides, the intracellular Ca2(+)-mobilizing caerulein and the cAMP-mediated secretin, and also the phosphodiesterase inhibitor caffeine on pancreatic secretion and growth in newborn rats. To investigate the secretory response of these substances, and to construct dose-response curves 10-...

journal_title：Zeitschrift fur Gastroenterologie

authors： Papp M,Ammann RW,Dobronyl I,Varga G

更新日期：1990-04-01 00:00:00

abstract：:Quantitative autoradiography was used to assess the densities of gamma-aminobutyric acid (GABAA) receptors in the brains of rats with a portacaval end-to-side shunt (PCA). The shunt alone induced only mild encephalopathy with ataxia and decreased locomotion. Aggravation of the encephalopathy was achieved by gavage fee...

journal_title：Zeitschrift fur Gastroenterologie

authors： Rössle M,Deckert J,Mullen KD,Jones DB,Grün M,Gerok W,Jones EA

更新日期：1990-03-01 00:00:00

abstract：:Depressed adenoma of the stomach, whose gross appearance is similar to that of type IIc early gastric carcinoma, was detected in 40/357, or 11%, of gastric resection preparations. Depressed adenoma is primarily found in the two distal thirds and the lesser curvature of the stomach. It presents as a flat brownish depre...

journal_title：Zeitschrift fur Gastroenterologie

authors： Ottenjann R

更新日期：1990-02-01 00:00:00

abstract：:Fibrolamellar hepatocellular carcinoma of the liver is a rare variant of hepatocellular carcinoma with characteristic morphological patterns and a good prognosis. Preoperatively the tumor is rarely diagnosed. Surgical treatment is resection, hemihepatectomy or transplantation of the liver. We report a case of a 51 yea...

journal_title：Zeitschrift fur Gastroenterologie

authors： Kahle M,Heilmann KL,Filler RD

更新日期：1989-06-01 00:00:00

abstract：:We studied intestinal zinc absorption and daily urinary zinc excretion in 13 healthy controls and 27 cirrhotic patients (14 alcoholics, 13 non-alcoholics) with normal serum creatinine levels. Intestinal zinc absorption was determined by the oral zinc tolerance test. Serum levels were significantly lower in cirrhotics,...

journal_title：Zeitschrift fur Gastroenterologie

authors： Solis-Herruzo J,De Cuenca B,Muñoz-Rivero MC

更新日期：1989-06-01 00:00:00

abstract：:The retention of 75Se-homotaurocholic acid (75SeHCAT) was measured in 12 healthy controls and in 21 patients with Crohn's disease and compared with the maximum postprandial rise in the serum concentration of cholylglycine (CG) in order to detect bile acid malabsorption. The retention of 75SeHCAT was lowered in all pat...

journal_title：Zeitschrift fur Gastroenterologie

authors： Karbach U,Singe CC,Mähtricht M,Ewe K

更新日期：1989-05-01 00:00:00

abstract：:A 45-years old man after having returned from Thailand was admitted to the hospital with a severe ulcerative, pyogenic colitis and multiple liver abscesses. In the endoscopically taken rectal biopsies as well as in the liver abscess aspirate gained by fine needle puncture Throphozoites of E. histolytica could be demon...

journal_title：Zeitschrift fur Gastroenterologie

authors： Bihl P,Hobik HP,Schmidt-Wilcke HA

更新日期：1989-02-01 00:00:00

abstract：:We prospectively compared esophageal and rectal motility data from 7 patients with progressive systemic sclerosis (4 females, 3 males) to esophageal recordings in 22 and anorectal recordings in 9 healthy controls. All patients with sclerosis exhibited motility disturbances in the lower esophageal sphincter (LES): LES ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Frieling T,Enck P,Bremer G,Lübke HJ,Berges W,Wienbeck M

更新日期：1988-11-01 00:00:00

abstract：:The metabolism of ethanol to acetaldehyde in the liver proceeds via alcohol dehydrogenase (ADH) and the microsomal ethanol-oxidizing system (MOS), whereas catalase plays no significant role. ADH is an enzyme of the cytosol, requires NAD+ as cofactor and exhibits a pH optimum in the alkaline range. The Km of ADH is abo...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gellert J,Teschke R

更新日期：1988-10-01 00:00:00

abstract：:During the last years the per-capita-consumption of pure alcohol in the Federal Republic of Germany is slightly decreasing. In 1986 every person consumed an average of 11.5 litres of pure alcohol (146.4 litres of beer, 23.3 litres of wine and 6.1 litres of spirits). The amount of the alcohol addicts must be estimated ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Ziegler H

更新日期：1988-10-01 00:00:00

abstract：:In 20 patients suffering from advanced chronic active hepatitis, type B or NANB, the therapeutic effect of cyclosporin A was studied. 15 of these patients already showed cirrhotic transformations and partial liver dysfunctions. In 15 cases an unsuccessful pretreatment with glucocorticoids and/or azathioprine had been ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Friedrich K,Henning H

更新日期：1988-05-01 00:00:00

abstract：:Quantitative liver function tests (QLFT), e.g. 1) galactose elimination capacity (GEK) and 2) fractional indocyanine-green elimination constant k (ICG) were performed in patients with various liver diseases. Retrospectively the results of QLFT were compared to clinical, histological and laboratory findings which are k...

journal_title：Zeitschrift fur Gastroenterologie

authors： Albers I,Hartmann H,Creutzfeldt W

更新日期：1988-02-01 00:00:00

abstract：:10 patients with right upper quadrant pain were treated with a choleretic agent (Febuprol; 3 X 200 mg t. i. d.) and placebo in a cross-over double dummy technique for 16 weeks. Lithogenic index, bile acid profile and serum lipids were determined every 4 weeks. During Febuprol application the clinical symptoms were rel...

journal_title：Zeitschrift fur Gastroenterologie

authors： Swobodnik W,Wechsler JG,Klüppelberg U,Janowitz P,Hutt V,Ditschuneit H

更新日期：1987-11-01 00:00:00

abstract：:The role of endogenous gastrin in the pathogenesis of "idiopathic" ulcer disease is difficult to determine; however, gastrin is probably only of limited importance besides various probable more important factors. In conditions associated with uncontrolled gastrin production by a gastrin secreting tumor or in cases in ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Koop H

更新日期：1987-08-01 00:00:00

abstract：:Somatostatin is located predominantly in D-cells of the antral and fundic area of the stomach and in the duodenal bulb. Furthermore, somatostatin is contained in neurons of the extrinsic and intrinsic nervous system. Somatostatin inhibits gastric acid, pepsin and gastrin secretion, and it stimulates gastric mucous sec...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schusdziarra V,Weigert N

更新日期：1987-08-01 00:00:00

abstract：:The role of bile acids and lysolecithin in the pathogenesis of peptic ulcer is as yet not unequivocally defined. Based on the physiochemical properties of bile acids and animal experiments they have damaging potential on the mucosal cell. However, the majority of results reported in patients do not favour a significan...

journal_title：Zeitschrift fur Gastroenterologie

authors： Schölmerich J

更新日期：1987-08-01 00:00:00

abstract：:In 20 patients with malignancies receiving abdominal radiotherapy, tests for disturbed intestinal functions were performed at the beginning and at the end of the therapy and after 6 to 12 month following radiation. Four noninvasive tests were performed: 75Se-homotaurocholate (75SeHCAT) test for estimation of bile acid...

journal_title：Zeitschrift fur Gastroenterologie

authors： Ruppin H,Hotze A,Düring A,Reichert M,Bauer J,Stoll R,Herbst M,Mahlstedt J

更新日期：1987-05-01 00:00:00

abstract：:A new method of exocrine pancreatic function testing is described. After oral administration of a standard meal containing fluorescein dilaurate (FDL) metoclopramide (10 mg) and secretin (1 U/kg) are given as intravenous bolus injection. The best discrimination between normal and abnormal pancreatic function was found...

journal_title：Zeitschrift fur Gastroenterologie

authors： Malfertheiner P,Büchler M,Müller A,Ditschuneit H

更新日期：1987-04-01 00:00:00

abstract：:In humans and many laboratory animals, protein and fat digestion products are potent intestinal stimulants of pancreatic enzyme secretion. Both neural and hormonal pathways mediate the enzyme response to these intestinal stimulants. Enteropancreatic, cholinergic, vago-vagal reflexes are probably the most important med...

journal_title：Zeitschrift fur Gastroenterologie

authors： Singer MV,Niebel W,Layer P

更新日期：1987-04-01 00:00:00

abstract：:The effects of surgical and chemical sympathectomy on various gastric functions was studied in rats. From the results it is concluded that the sympatho-adrenal system inhibits gastric acid secretion and mucosal blood flow. The regulation of pepsin secretion by the sympathetic nervous system appears controversial: unde...

journal_title：Zeitschrift fur Gastroenterologie

authors： Hanisch E,Hottenrott C,Encke A

更新日期：1987-04-01 00:00:00

abstract：:Atrophy of the small intestinal mucosa is functionally characterized by a reduction in non-electrolyte transport in vivo. In order to elucidate the cellular defect being responsible for this malabsorption, we have studied the Na+-dependent D-glucose accumulation as well as the activities of aminopeptidase M and maltas...

journal_title：Zeitschrift fur Gastroenterologie

authors： Menge H,Stange G,Murer H

更新日期：1986-11-01 00:00:00

abstract：:The problem of the pathogenetic significance of IgE-mediated inflammatory processes in simple unspecific gastritis was studied in mucosal biopsies of 396 cases with unequivocal histological classification. The results demonstrate that only in acute and erosive gastritis high IgE cell counts are found, thus, indicating...

journal_title：Zeitschrift fur Gastroenterologie

authors： Dukat H,Dumke K,Niedobitek F,Volkheimer G

更新日期：1986-11-01 00:00:00

abstract：:The gene structure of human cholecystokinin (CCK) is known and the cDNA structures are known for pig and rat. However, the molecular forms of CCK produced, stored and released from neural or endocrine cells cannot be predicted from the known structures of preprocholecystokinin derived from cDNA. It is well recognized ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Eysselein VE,Reeve JR Jr,Eberlein G

更新日期：1986-10-01 00:00:00

abstract：:1977 cases with gastric complains but without localized findings like ulcer or cancer were investigated by gastroscopy with biopsies of corpus and antrum ventriculi. We found in 5.5% an isolated mucosal atrophy of the gastric corpus (mean age 67.2 years compared to 59.4 years in cases with normal mucosa). 0.7% showed ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Witte S,Langer J,Stolte M

更新日期：1986-07-01 00:00:00

abstract：:In a randomized, endoscopically controlled double-blind trial the effectiveness of a twice daily dose of the prostaglandin E2-analogue enprostil was compared with pirenzepine given to 97 ambulatory patients with duodenal ulcers. Under 35 micrograms b.i.d. enprostil the ulcer healing rates after 2, 4 and 6 weeks averag...

journal_title：Zeitschrift fur Gastroenterologie

authors： Rohner HG,Beckenbach HP,Daake H,Dammann HG,Hüttemann R,Kalek S,Kühn V,Müller P,Simon B

更新日期：1986-05-01 00:00:00

abstract：:The spontaneous course of the galactosamine-hepatitis in the guinea-pig (750 and 1000 mg/kg GalN iv respectively) is characterized by a terminal hypoglycemia together with hypothermia and arterial hypotension fifty-nine hours on average after GalN-application. Preventing hypoglycemia and hypothermia by continuous intr...

journal_title：Zeitschrift fur Gastroenterologie

authors： Brachtel D,Richter E

更新日期：1986-04-01 00:00:00

abstract：:The application of Penicillamine (750 mg per day) for one year resulted in the expected increase of urinary copper excretion (8-10 fold). The increase of Zinc excretion was only moderate (2 fold). The application of Penicillamine did not influence the excretion of Ca, Mg and Fe. We did not find a decrease of Zinc cont...

journal_title：Zeitschrift fur Gastroenterologie

authors： Dastych M,Jezek P,Richtrová M

更新日期：1986-03-01 00:00:00